The bridge that bacteria build

RICHA AGRAWAL

Jul 2023
from Shaastra :: vol 02 issue 04 :: Jul - Aug 2023

A cryo-electron microscopy image of gut bacteria exchanging antimicrobial resistance genes through the F-pilus bridges.

A study finds that a molecule called PG phospholipid shields bacteria from antibiotics.

The F-pilus Bridge intrigued the scientists. It didn't snap when bent to almost 180 degrees. Testing its strength and resilience in harsh chemical environments, they applied a force that typically unzips or breaks the structure of most proteins. The bridge, however, went on to exhibit spring-like properties. The team boiled it in highly concentrated urea, a chemical known to deform proteins. The bridge held its own.